Acne Care Powered by Precision Science
Introducing our newest breakthrough in precision skincare: the patented CUT-02™ enzyme targets acne-causing bacteria without disrupting the skin’s microbiome, delivering proven clinical results that stack up against the leading acne treatments—all without harsh side effects.
Precision Acne Care Powered by CUT-02™
Introducing our newest breakthrough in precision science: the patented CUT-02™ enzyme targets acne-causing bacteria without disrupting the skin’s microbiome, delivering proven clinical results that stack up against the leading acne treatments—all without harsh side effects.
THE CUT-02™ ENZYME, EXPLAINED
01
Targets acne at the source
The patented CUT-02™ enzyme specifically eliminates C. acnes, the bacteria responsible for acne. That means lasting reductions in breakouts, inflammation, and redness.
02
Clear skin without the trade-offs
Traditional acne treatments come with a long list of harsh side effects and destroy the skin’s microbiome. Because CUT-02™ targets only acne-causing bacteria, it delivers real results without disrupting skin
03
Precision care that balances the microbiome
Acne-prone skin isn't just oily skin, it's a microbiome imbalance. CUT-02™ helps restore the naturally protective bacterial ecosystem that healthy skin depends on.
ACNE PRECISION SERUM
99.9%
of C. acnes bacteria killed within 1 hour without harming beneficial bacteria*
93%
of people saw improvement in acne symptoms after 2 weeks**
89%
said their skin had less redness**
95%
said it was non-irritating**
*Based on in vitro data of CUT-02™ enzyme
**Based on an 8-week clinical trial of 19 adults with very mild to severe acne
DAILY ACNE CLEANSER
100%
saw reduced acne symptoms within 2 weeks of use*
100%
saw reduced skin oiliness after 4 weeks of use*
91%
reported cleaner pores after 4 weeks of use*
91%
said the cleanser is gentle enough to use twice a day*
*Based on a clinical trial of 32 adults with mild to severe acne (sebumetry measurements)
PRECISION MICRODART BLEMISH PATCHES
97%
said the patch helped flatten the pimple in 8 hours.*
84%
reported the patch worked faster than their usual spot treatment.*
94%
said the patch reduced the redness of the pimple in 8 hours.*
88%
said the patch stopped the progression of the pimple.*
*Based on a clinical trial of 32 adults with under-the-surface pimples
ACNE PRECISION SERUM
99.9%
of C. acnes bacteria killed within 1 hour without harming beneficial bacteria*
93%
of people saw improvement in acne symptoms after 2 weeks**
89%
said their skin had less redness**
95%
said it was non-irritating**
*Based on in vitro data of CUT-02™ enzyme
**Based on an 8-week clinical trial of 19 adults with very mild to severe acne
DAILY ACNE CLEANSER
100%
saw reduced acne symptoms within 2 weeks of use*
100%
saw reduced skin oiliness after 4 weeks of use*
91%
reported cleaner pores after 4 weeks of use*
91%
said the cleanser is gentle enough to use twice a day*
*Based on a clinical trial of 32 adults with mild to severe acne (sebumetry measurements)
PRECISION MICRODART BLEMISH PATCHES
97%
said the patch helped flatten the pimple in 8 hours.*
84%
reported the patch worked faster than their usual spot treatment.*
94%
said the patch reduced the redness of the pimple in 8 hours.*
88%
said the patch stopped the progression of the pimple.*
*Based on a clinical trial of 32 adults with under-the-surface pimples
Expert Perspectives
THE HYPOTHESIS™ ACNE ROUTINE
A daily regimen built around the power of CUT-02™—designed for real results with none of the harsh side effects.
GENTLE EXFOLIATION
Daily Acne Cleanser
Exfoliates clogged pores and dissolves excess oil, treating acne without drying the skin’s naturally protective barrier.
CLEAR SKIN
Acne Precision Serum
Kills acne-causing bacteria with our patented CUT-02™ enzyme, preventing future acne without disrupting your skin’s beneficial microbiome.
SPOT TREAT
Precision Microdart Blemish Patches
Visibly flatten under-the-surface pimples in 8 hours with patented CUT-02™ and our innovative microdart delivery method.
Learn More About Hypothesis™
For deeper background on the science behind CUT-02™, hypothesis™ co-founder Oliver Liu, PhD, explains the microbiome research behind the range, the C. acnes subtypes that drive acne, and the reason why precision targeting produces better long-term outcomes than conventional acne treatments.
Acne and the Microbiome: Why Precision Is the Future of Acne Care
By Oliver Liu, PhD
Skin Anarchy Podcast
Precision Care for Acne and Eczema with Oliver Liu of Hypothesis™
DOWNLOAD PRESS MATERIALS
Learn More About Hypothesis™
For deeper background on the science behind CUT-02™, hypothesis™ co-founder Oliver Liu, PhD, explains the microbiome research behind the range, the C. acnes subtypes that drive acne, and the reason why precision targeting produces better long-term outcomes than conventional acne treatments.
Acne and the Microbiome: Why Precision Is the Future of Acne Care
By Oliver Liu, PhD
Skin Anarchy Podcast
Precision Care for Acne and Eczema with Oliver Liu of Hypothesis™
DOWNLOAD PRESS MATERIALS