Acne Care Powered by Precision Science
Introducing our newest breakthrough in precision skincare: the patented CUT-02™ enzyme targets acne-causing bacteria without disrupting the skin’s microbiome, delivering proven clinical results that stack up against the leading acne treatments—all without harsh side effects.
Precision Acne Care Powered by CUT-02™
Introducing our newest breakthrough in precision science: the patented CUT-02™ enzyme targets acne-causing bacteria without disrupting the skin’s microbiome, delivering proven clinical results that stack up against the leading acne treatments—all without harsh side effects.
THE CUT-02™ ENZYME, EXPLAINED
01
Targets acne at the source
The patented CUT-02™ enzyme specifically eliminates C. acnes, the bacteria responsible for acne. That means lasting reductions in breakouts, inflammation, and redness.
02
Clear skin without the trade-offs
Traditional acne treatments come with a long list of harsh side effects and destroy the skin’s microbiome. Because CUT-02™ targets only acne-causing bacteria, it delivers real results without disrupting skin
03
Precision care that balances the microbiome
Acne-prone skin isn't just oily skin, it's a microbiome imbalance. CUT-02™ helps restore the naturally protective bacterial ecosystem that healthy skin depends on.
DAILY ACNE CLEANSER
100%
saw reduced acne symptoms within 2 weeks of use*
100%
saw reduced skin oiliness after 4 weeks of use*
91%
reported cleaner pores after 4 weeks of use*
91%
said the cleanser is gentle enough to use twice a day*
*Based on a clinical trial of 32 adults with mild to severe acne (sebumetry measurements)
ACNE PRECISION SERUM
99.9%
of C. acnes bacteria killed within 1 hour without harming beneficial bacteria*
93%
of people saw improvement in acne symptoms after 2 weeks**
89%
said their skin had less redness**
95%
said it was non-irritating**
*Based on in vitro data of CUT-02™ enzyme
**Based on an 8-week clinical trial of 19 adults with very mild to severe acne
BALANCING + BRIGHTENING GEL CREAM
100%
experienced skin barrier regeneration after a single use*
100%
experienced instant hydration*
97%
experienced a reduction in redness after 4 weeks**
*Based on a clinical trial of 31 adults with mild to severe acne
** Based on a clinical trial of 32 adults with mild to severe acne
PRECISION CLARIFYING SPRAY
99.9%
of C. acnes bacteria killed within 1 hour without harming beneficial bacteria*
100%
experienced skin barrier regeneration after a single use**
97%
experienced instant hydration**
*Based on a clinical trial of 32 adults with under-the-surface pimples
PRECISION MICRODART BLEMISH PATCHES
97%
said the patch helped flatten the pimple in 8 hours.*
84%
reported the patch worked faster than their usual spot treatment.*
94%
said the patch reduced the redness of the pimple in 8 hours.*
88%
said the patch stopped the progression of the pimple.*
*Based on a clinical trial of 32 adults with under-the-surface pimples
DAILY ACNE CLEANSER
100%
saw reduced acne symptoms within 2 weeks of use*
100%
saw reduced skin oiliness after 4 weeks of use*
91%
reported cleaner pores after 4 weeks of use*
91%
said the cleanser is gentle enough to use twice a day*
*Based on a clinical trial of 32 adults with mild to severe acne (sebumetry measurements)
ACNE PRECISION SERUM
99.9%
of C. acnes bacteria killed within 1 hour without harming beneficial bacteria*
93%
of people saw improvement in acne symptoms after 2 weeks**
89%
said their skin had less redness**
95%
said it was non-irritating**
*Based on in vitro data of CUT-02™ enzyme
**Based on an 8-week clinical trial of 19 adults with very mild to severe acne
BALANCING + BRIGHTENING GEL CREAM
100%
experienced skin barrier regeneration after a single use*
100%
experienced instant hydration*
97%
experienced a reduction in redness after 4 weeks**
*Based on a clinical trial of 31 adults with mild to severe acne
** Based on a clinical trial of 32 adults with mild to severe acne
PRECISION CLARIFYING SPRAY
99.9%
of C. acnes bacteria killed within 1 hour without harming beneficial bacteria*
100%
experienced skin barrier regeneration after a single use**
97%
experienced instant hydration**
*Based on a clinical trial of 32 adults with under-the-surface pimples
PRECISION MICRODART BLEMISH PATCHES
97%
said the patch helped flatten the pimple in 8 hours.*
84%
reported the patch worked faster than their usual spot treatment.*
94%
said the patch reduced the redness of the pimple in 8 hours.*
88%
said the patch stopped the progression of the pimple.*
*Based on a clinical trial of 32 adults with under-the-surface pimples
Expert Perspectives
Acne Care Reimagined. Powered by CUT-02™.
YOUR DAILY ROUTINE
Use morning and night to treat and prevent acne.
WHEN SKIN NEEDS IT
Apply anytime to restore skin to its balanced state.
YOUR DAILY ROUTINE
Use morning and night to treat and prevent acne.
WHEN SKIN NEEDS IT
Apply anytime to restore skin to its balanced state.
Learn More About Hypothesis™
For deeper background on the science behind CUT-02™, hypothesis™ co-founder Oliver Liu, PhD, explains the microbiome research behind the range, the C. acnes subtypes that drive acne, and the reason why precision targeting produces better long-term outcomes than conventional acne treatments.
Acne and the Microbiome: Why Precision Is the Future of Acne Care
By Oliver Liu, PhD
Skin Anarchy Podcast
Precision Care for Acne and Eczema with Oliver Liu of Hypothesis™
DOWNLOAD PRESS MATERIALS
Learn More About Hypothesis™
For deeper background on the science behind CUT-02™, hypothesis™ co-founder Oliver Liu, PhD, explains the microbiome research behind the range, the C. acnes subtypes that drive acne, and the reason why precision targeting produces better long-term outcomes than conventional acne treatments.
Acne and the Microbiome: Why Precision Is the Future of Acne Care
By Oliver Liu, PhD
Skin Anarchy Podcast
Precision Care for Acne and Eczema with Oliver Liu of Hypothesis™
DOWNLOAD PRESS MATERIALS