Peter Lio, MD, FAAD is a Clinical Assistant Professor of Dermatology & Pediatrics at Northwestern University Feinberg School of Medicine and an adjunct Clinical Professor of Dermatology at the Icahn School of Medicine at Mount Sinai. Dr. Lio received his medical degree from Harvard Medical School, completed his internship in Pediatrics at Boston Children’s Hospital, and his Dermatology training at Harvard.

Dr. Lio is the founding director of the Chicago Integrative Eczema Center and a founding partner of Medical Dermatology Associates of Chicago. He serves as a board member and scientific advisory committee member emeritus for the National Eczema Association. He is a member of the American Academy of Dermatology’s Atopic Dermatitis Expert Resource Group, a Councilor for the International Eczema Council, and a founding faculty member of the Integrative Dermatology Certificate Program.

Why Hypothesis
“Effective long-term eczema care depends on more than just treating inflammation and itch—it means restoring and preserving a healthy skin microbiome."

Dr. Yu is a dual-board certified adult and pediatric dermatologist specializing in allergic contact dermatitis and atopic dermatitis. He completed his pediatric internship at Massachusetts General Hospital, dermatology residency at Medical College of Wisconsin, and pediatric dermatology fellowship at Children's Hospital of Philadelphia. Dr. Yu served as Director of Contact Dermatitis and Atopic Dermatitis clinics at Massachusetts General Hospital/Harvard Medical School for 8 years prior to moving back to his home state of Virginia.

Dr. Yu is currently Chair of Dermatology at Virginia Commonwealth University in Richmond, VA where he leads the contact dermatitis and atopic dermatitis clinics. Dr. Yu is the President of the American Contact Dermatitis Society and is passionate about running clinical trials and partnering with industry to bring novel therapies to patients with dermatologic conditions.

Why Hypothesis
“We've never had an enzyme like TPZ-01™ before that can control one particular species of bacteria on skin. It's a phenomenon in precision medicine that will bring benefits to countless patients with eczema.” 

Omer Ibrahim, MD, MBA is a board-certified, fellowship-trained dermatologist and CEO of KGL Skin Study Center. He received his medical degree from Yale School of Medicine, completed dermatology residency at the Cleveland Clinic, and pursued an American Society for Dermatologic Surgery–accredited fellowship in cosmetic, laser, and dermatologic surgery at SkinCare Physicians (Boston). 

Dr. Ibrahim specializes in aesthetic dermatology, hair loss medicine, and cutting-edge clinical research. He also serves as adjunct faculty at the Cleveland Clinic and Rush University, where he trains residents in cosmetic and surgical dermatology. Dr. Ibrahim has over 100 publications including peer-reviewed articles, book chapters, and abstracts. 

Why Hypothesis
"Eczema care must be safe, effective, and gentle, especially for children. The patented TPZ-01™ enzyme offers families a steroid-free solution that eliminates Staph aureus bacteria while preserving beneficial microbes for lasting relief without side effects."

Elbert H Chen, MD, FAAD, FACMS is a double board-certified dermatologist and micrographic dermatologic surgeon. He graduated magna cum laude from Harvard University with a degree in Biochemical Sciences and subsequently attended Duke University School of Medicine. Dr. Chen graduated with highest honors from Duke and pursued his dermatology training at Yale University School of Medicine, where he served as Chief Resident during his final year. 

Dr. Chen completed his training with a two-year fellowship in Mohs Micrographic Surgery and Procedural Dermatology at Columbia College of Physicians and Surgeons. He is currently chief of Mohs Surgery at The Permanente Medical Group in Northern California.

Why Hypothesis
“The TPZ-01™ enzyme represents a real scientific breakthrough. It works by specifically targeting Staph aureus bacteria, which helps restore the balance of the skin’s microbiome.”