







ECZEMA PRECISION KIT
A set of travel-sized skin-soothing eczema essentials
Your complete eczema care routine in travel-friendly sizes. This duo targets flare-ups at their source, with our patented TPZ-01™ enzyme that specifically eliminates Staph aureus bacteria while restoring your skin's natural balance. Our Eczema Precision Hydrogel delivers lasting relief, while our Eczema Therapy Cream replenishes your skin barrier and locks in moisture. Together, they soothe itching and reduce irritation for real relief.
2-piece Eczema Precision Kit includes:
Eczema Precision Hydrogel 30 mL
Eczema Therapy Cream 30 mL
Free shipping on US orders over $50
Details








Ingredients
How To Use








ECZEMA THERAPY CREAM
This deeply hydrating moisturizer is designed to work in parallel with the Eczema Precision Hydrogel to repair the skin barrier. Made with 1% colloidal oatmeal and ceramides, this pH-balanced formula relieves the itch of eczema and supports an optimal pH level for a healthy microbiome.

ECZEMA PRECISION HYDROGEL
Made with our patented TPZ-01™ enzyme, this lightweight hydrogel is the first eczema treatment to address the skin’s microbiome imbalance head on, targeting and killing eczema-associated Staph aureus bacteria to break the cycle of damage and irritation so skin can finally heal.



ECZEMA THERAPY CREAM
This deeply hydrating moisturizer is designed to work in parallel with the Eczema Precision Hydrogel to repair the skin barrier. Made with 1% colloidal oatmeal and ceramides, this pH-balanced formula relieves the itch of eczema and supports an optimal pH level for a healthy microbiome.
ECZEMA PRECISION HYDROGEL
Made with our patented TPZ-01™ enzyme, this lightweight hydrogel is the first eczema treatment to address the skin’s microbiome imbalance head on, targeting and killing eczema-associated Staph aureus bacteria to break the cycle of damage and irritation so skin can finally heal.






Eczema Precision Hydrogel
Relieves irritation + itching from eczema


RESULTS
2.5x
more effective than a standard eczema treatment*
85%
reduction in eczema-associated Staph aureus bacteria on the skin*
100%
of participants saw reduced eczema symptoms within 2 weeks*
*Based on a 2-week clinical trial of 24 adults with moderate to severe eczema comparing Hypothesis Eczema Precision Hydrogel to a product containing over-the-counter levels of colloidal oatmeal.
Eczema Therapy Cream
Hydrates dry skin + restores the skin barrier


RESULTS
96%
said it nourished and improved dry skin*
91%
saw improved hydration for 24 hours after a single use*
100%
of participants saw immediate improvement in skin barrier function that lasted all day**
*Based on a 7-day clinical study of 34 adults with dry skin.
**Based on a clinical trial of 33 adults with damaged skin barriers.
I love the texture of the hydrogel. It soothes my skin and applies very easily…can put it on right before bed or right before applying makeup. My redness and flakiness have improved and feels so much better.
Not gonna lie, I stole some of this cream I got for my daughter for myself!…Helps relieve the tightness and soothes the cracks both she and I get. It feels rich and thick—we both really enjoy using it!


Smart Science, By Design




FAQS
How is this different from other eczema treatments?
Studies show that people with eczema have much higher levels of a bacteria called Staphylococcus aureus on their skin, particularly during flare-ups. Once on the skin, Staphylococcus aureus—also known as Staph, Staph aureus, or S. aureus—can secrete toxins that damage the skin barrier, increase itching, and activate the immune system. The more Staph aureus on skin, the more severe the eczema symptoms—yet standard eczema treatments like moisturizers and steroid creams do not address this underlying imbalance in the eczema skin microbiome.
At Hypothesis, we’re using the science of biotechnology to develop clinically validated skincare that tackles the eczema microbiome head on. Our patented TPZ-01™ precision enzyme targets and kills eczema-associated Staph aureus bacteria while preserving the rest of your skin’s helpful microbiome, helping to reestablish a healthy, balanced microbiome that breaks the cycle of itching, skin barrier damage, and flare-ups.
Does the Eczema Precision Hydrogel contain steroids or fragrance?
All Hypothesis products are both steroid-free and fragrance-free. We avoid known irritants in our formulas and use rigorously screened, cutting-edge ingredients with proven track records of both gentleness and efficacy. Our clinically tested formulas are dermatologist-approved, accepted by the National Eczema Association (NEA), EWG Verified™, certified Microbiome Friendly by MyMicrobiome for both infants and adults with eczema, safe for use in the delicate eye area, and hypoallergenic.
Where can I apply Hypothesis products?
The Eczema Precision Hydrogel and Eczema Therapy Cream can be applied anywhere externally on your face or body where you’re experiencing eczema symptoms, including eyelids. As with all our products, this formula is safe for use around the eyes, dermatologist approved, and accepted by the National Eczema Association (NEA). We recommend applying liberally to itchy, irritated, or dry skin, or anywhere you typically have eczema flare-ups.
As with all new skincare products, we recommend doing a patch test before first use, especially if you have very sensitive skin or known allergies. Apply a small amount to an area like the inside of your wrist or behind your ear, wait 24 hours, and check for any reaction before applying to larger areas or your face.
How do I use Hypothesis products in my daily routine?
We recommend using our Eczema Precision Hydrogel with our patented TPZ-01™ precision enzyme at least twice a day (morning and night), but more often if needed for additional soothing. Our Precision Healing Spray with TPZ-01™ is a convenient spray format designed for quick application to hard-to-reach areas or on-the-go use throughout the day. It can be used as a standalone soothing spray, or used in conjunction with our Eczema Precision Hydrogel for a double dose of the TPZ-01™ enzyme. Our Eczema Therapy Cream is a moisturizer designed to work in tandem with the TPZ-01™ enzyme, and can be used after the Precision Healing Spray or Eczema Precision Hydrogel to seal in additional moisture. Apply the Eczema Therapy Cream any time your skin needs immediate hydration or skin barrier repair.
How long does it take to see results?
In clinical studies of the Eczema Precision Hydrogel, most users saw initial improvement in their eczema symptoms within a week, with best results after 2–4 weeks of twice-daily use. The Eczema Therapy Cream immediately hydrates and strengthens the skin barrier with benefits that last all day.
Is the Eczema Precision Hydrogel safe for babies and children?
Yes, all of our hypoallergenic, dermatologist-approved formulas are extensively tested by independent certifying organizations to meet the highest standards for safety and gentleness on sensitive skin. Our formulas are steroid-free and fragrance-free, have received the National Eczema Association (NEA) Seal of Acceptance, and are EWG Verified™ for meeting stringent standards for safety and sustainability. Our products are also certified Microbiome Friendly by MyMicrobiome for both infants and adults.
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Clinically tested, next-generation formulas that treat the bacteria behind flare-ups to visibly transform skin.