ECZEMA PRECISION HYDROGEL

Studies show that people with eczema have much higher levels of a bacteria called Staphylococcus aureus on their skin, particularly during flare-ups.  Once on the skin, Staphylococcus aureus—also known as Staph, Staph aureus, or S. aureus—can secrete toxins that damage the skin barrier, increase itching, and activate the immune system. The more Staph aureus on skin, the more severe the eczema symptoms—yet standard eczema treatments like moisturizers and steroid creams do not address this underlying imbalance in the eczema skin microbiome.

 At Hypothesis, we’re using the science of biotechnology to develop clinically validated skincare that tackles the eczema microbiome head on. Our patented TPZ-01™ precision enzyme targets and kills eczema-associated Staph aureus bacteria while preserving the rest of your skin’s helpful microbiome, helping to reestablish a healthy, balanced microbiome that breaks the cycle of itching, skin barrier damage, and flare-ups.

All Hypothesis products are both steroid-free and fragrance-free. We avoid known irritants in our formulas and use rigorously screened, cutting-edge ingredients with proven track records of both gentleness and efficacy. Our clinically tested formulas are dermatologist-approved, accepted by the National Eczema Association (NEA), EWG Verified®, certified Microbiome Friendly by MyMicrobiome for both infants and adults with eczema, safe for use in the delicate eye area, and hypoallergenic.

The Eczema Precision Hydrogel is fragrance-free. We avoid known irritants in our formulas and use rigorously screened, cutting-edge ingredients with proven track records of both gentleness and efficacy. You may notice a mild, naturally-occurring scent from the amino acid methionine. Methionine is an antioxidant that helps maintain the stability of our patented TPZ-01™ enzyme while protecting the skin from free radicals and supporting the skin barrier. Rather than covering this natural scent with potentially irritating synthetic fragrances or chemical masking agents, we choose to keep our formula as streamlined as possible to minimize irritation. Methionine's scent is completely normal and should quickly fade as the formula absorbs into your skin.

The Eczema Precision Hydrogel can be applied anywhere externally on your face or body where you’re experiencing eczema symptoms, including eyelids. As with all our products, this formula is safe for use around the eyes, dermatologist approved, and accepted by the National Eczema Association (NEA). We recommend applying liberally to itchy, irritated, or dry skin, or anywhere you typically have eczema flare-ups.

As with all new skincare products, we recommend doing a patch test before first use, especially if you have very sensitive skin or known allergies. Apply a small amount to an area like the inside of your wrist or behind your ear, wait 24 hours, and check for any reaction before applying to larger areas or your face.

We recommend using our Eczema Precision Hydrogel with our patented TPZ-01™ precision enzyme at least twice a day (morning and night), but more often if needed for additional soothing. Our Precision Healing Spray with TPZ-01™ is a convenient spray format designed for quick application to hard-to-reach areas or on-the-go use throughout the day. It can be used as a standalone soothing spray, or used in conjunction with our Eczema Precision Hydrogel for a double dose of the TPZ-01™ enzyme. Our Eczema Therapy Cream is a moisturizer designed to work in tandem with the TPZ-01™ enzyme, and can be used after the Precision Healing Spray or Eczema Precision Hydrogel to seal in additional moisture. Apply the Eczema Therapy Cream any time your skin needs immediate hydration or skin barrier repair. 

In clinical studies of the Eczema Precision Hydrogel, most users saw initial improvement in their eczema symptoms within a week, with best results after 2–4 weeks of twice-daily use.

Yes, all of our hypoallergenic, dermatologist-approved formulas are extensively tested by independent certifying organizations to meet the highest standards for safety and gentleness on sensitive skin. Our formulas are steroid-free and fragrance-free, have received the National Eczema Association (NEA) Seal of Acceptance, and are EWG Verified® for meeting stringent standards for safety and sustainability. Our products are also certified Microbiome Friendly by MyMicrobiome for both infants and adults.