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Exfoliates + clears clogged pores
Our daily purifying cleanser exfoliates clogged pores and dissolves excess oil, treating acne without drying the skin barrier or disrupting the skin’s natural balance. Designed to work in parallel with our patented CUT-02™ enzyme, this cleanser is clinically proven to reduce oiliness, acne, redness, and pore appearance.
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Benefits
Dermatologist Approved
Hypoallergenic
Safe for Eye AreaNo Added
Ingredients
How To Use










KEY INGREDIENTS
1% Salicylic Acid
An FDA-approved acne-fighting ingredient that gently exfoliates inside the pore to dissolve excess oil and dead skin cells, helping to clear breakouts and prevent new ones from forming.
Glycolic Acid
A powerful but gentle alpha hydroxy acid (AHA) that exfoliates and helps to even skin tone and fade discoloration from acne.
Zinc
This anti-inflammatory mineral helps lower sebum production and can help inhibit the growth of C. acnes bacteria.
Tea Tree Oil
Derived from the tea tree plant, this ingredient features antioxidant, antibacterial, and anti-inflammatory properties to purify and help calm inflamed skin.

KEY INGREDIENTS
1% Salicylic Acid
An FDA-approved acne-fighting ingredient that gently exfoliates inside the pore to dissolve excess oil and dead skin cells, helping to clear breakouts and prevent new ones from forming.
Glycolic Acid
A powerful but gentle alpha hydroxy acid (AHA) that exfoliates and helps to even skin tone and fade discoloration from acne.
Zinc
This anti-inflammatory mineral helps lower sebum production and can help inhibit the growth of C. acnes bacteria.
Tea Tree Oil
Derived from the tea tree plant, this ingredient features antioxidant, antibacterial, and anti-inflammatory properties to purify and help calm inflamed skin.



INGREDIENTS
Every ingredient we use is thoughtfully chosen for its clinically proven ability to clear and prevent acne, strengthen the skin's protective barrier, and support a healthy microbiome balance. Our groundbreaking formulas deliver lasting, real results you can see, and are rigorously tested and approved by dermatologists for both efficacy and gentleness.
INGREDIENTS
Every ingredient we use is thoughtfully chosen for its clinically proven ability to clear and prevent acne, strengthen the skin's protective barrier, and support a healthy microbiome balance. Our groundbreaking formulas deliver lasting, real results you can see, and are rigorously tested and approved by dermatologists for both efficacy and gentleness.
Real People, Real Results


Clinically Proven to Reduce Acne Without Irritation in 2 Weeks

100 %
saw reduced acne symptoms within 2 weeks of use*
100 %
saw reduced skin oiliness after 4 weeks of use*
91 %
reported cleaner pores after 4 weeks of use*
91 %
said the cleanser is gentle enough to use twice a day*
*Based on a clinical trial of 32 adults with mild to severe acne (sebumetry measurements)


FAQS
Does the Daily Acne Cleanser contain benzoyl peroxide?
All hypothesis™ products, including the Daily Acne Cleanser, are benzoyl peroxide-free and benzene-free. We avoid known irritants in our formulas and use rigorously screened, cutting-edge ingredients with proven track records of both gentleness and efficacy. Our targeted, clinically tested formulas are dermatologist-approved, microbiome-friendly, hypoallergenic, non-comedogenic, and non-irritating to eyes.
Does the Daily Acne Cleanser contain fragrance?
Our acne products contain no added fragrances. You may notice that the tea tree oil in our Daily Acne Cleanser formula has a mild herbal aroma. This functional ingredient has antioxidant, antibacterial, and anti-inflammatory properties to purify and help calm inflamed skin. We choose not to add unnecessary ingredients to mask our formulas’ natural aromas.
Where can I apply the Daily Acne Cleanser?
The Daily Acne Cleanser can be applied anywhere on your face or body where you’re experiencing breakouts. As with all our products, our acne formulas are safe for use around the eyes, dermatologist approved, and rigorously clinically tested for safety and efficacy. We recommend applying liberally to irritated, acne-prone skin, or anywhere you typically have acne blemishes.
How do I use hypothesis™ acne products in my daily routine?
Start with one application daily: in the evening, cleanse skin with the Daily Acne Cleanser, then apply the Acne Precision Serum. Once the Acne Precision Serum has fully absorbed into the skin, apply a moisturizer as needed and leave on overnight. Increase to twice daily application (morning and evening) if well-tolerated. Apply Precision Microdart Blemish Patches as needed to clean, dry skin to address early, under-the-surface pimples.
Our acne products are designed to work synergistically with one another, and the Daily Acne Cleanser is specifically formulated to be compatible with our precision acne products with the CUT-02™ enzyme. If you use other serums or treatments in your regimen, we recommend applying them after the Daily Acne Cleanser and before the Acne Precision Serum.
Note: As products with salicylic acid can increase your skin’s sun sensitivity, use an SPF during the day.
How long does it take to see results?
You should typically start to see improvements within one to two weeks, with the most substantial results building over the full 8 weeks — particularly during weeks 4–8. In our 8-week clinical trial, 71% of participants noticed improvement after one week and 93% saw a reduction in acne within two weeks. Over the full 8 weeks, participants reported reduced oiliness, redness, and comedones, as well as more even skin tone.
As with many acne treatments, consistent daily use is key — it takes time for the microbiome to rebalance and inflammation to calm.
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Clinically tested formulas that specifically target and kill the bacteria behind acne, leaving your skin’s beneficial microbiome balanced and restored.













