ECZEMA + THE MICROBIOME
The skin’s microbiome is an ecosystem in miniature, with countless microorganisms living on and within our skin.
Microbiome protects skin
When the microbiome is in balance, beneficial microbes help to fortify the skin barrier, defend against infections, and train the body’s immune system to recognize threats and reduce inflammation.
Staph bacteria takes over
The skin microbiome of people with eczema is dramatically different from healthy skin microbiomes—and is dominated by a harmful bacteria called Staphylococcus aureus, Staph aureus, or S. aureus.
Staph drives flare-ups
Once on the skin, Staph aureus is like fuel on the fire, producing toxins that break down the skin barrier, cause itching and inflammation, and drive a cycle of increasing irritation and damage. If triggers like allergens, irritants, and stress are the matches, Staph aureus is the gasoline that turns that initial spark into a full blown flare-up.
TPZ-01™ targets Staph
Conventional eczema treatments fail to address the central role Staph aureus plays in eczema. Our high-precision TPZ-01™ enzyme is designed to selectively target and kill Staph aureus while preserving beneficial microbes.
TPZ-01™ enzyme rebalances the microbiome
Through our breakthrough precision technology, the TPZ-01™ enzyme helps to restore a healthy, balanced microbiome, breaking the cycle that drives flare-ups for real, lasting eczema relief.
How TPZ-01™ Is Different
Dermatologists have long known the connection between Staph aureus and eczema, but they haven't had the tools to do much about it. Antibiotics can damage healthy skin and gut microbiomes, and treatments like steroid creams do nothing to address microbiome imbalances. Reducing Staph aureus bacteria is both the biggest gap and biggest opportunity for better eczema treatments. TPZ-01™ finally fills this gap, addressing the eczema microbiome head on. It's a key addition to your existing eczema regimen, not only reducing symptoms but killing the bacteria that cause those symptoms in the first place.





The TPZ-01™ enzyme, explained
01
Real + long-lasting relief
Our patented TPZ-01™ enzyme specifically targets Staph aureus, the harmful bacteria that dominate the eczema microbiome—which means lasting, meaningful reductions in flare-ups, redness and irritation.
02
Supports a healthy microbiome
The TPZ-01™ enzyme preserves beneficial microbes, working with the microbiome and not against it. Re-establishing a balanced microbiome means the skin has a better defense system and a strengthened skin barrier.
03
Soothing without side effects
Because our patented TPZ-01™ enzyme focuses on repairing the microbiome, it provides relief without the side effects of traditional eczema treatments like steroid creams.